Cultural differences, as has been said, can contribute to misunderstandings, misinterpretations, misperceptions

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Cultural differences, as has been said, can contribute to misunderstandings, misinterpretations, misperceptions, and miscommunication, all of which can exacerbate conflict or reduce the chances of conflict being resolved. In many conflict situations, the parties fail to understand what these differences are and how they bear on the process itself and resolution of the conflict. What can you do to improve this situation, fraught with the danger of undermining any resolution of conflict? Certainly one, if not the most potent answer, is to understand how and be aware of the degree to which culture plays a role in conflict and conflict resolution, and then to act on this awareness and understanding accordingly. Chapter 28 in your text addresses the first half of this equation: awareness and understanding; Chapter 29 addresses the second: acting on the awareness and understanding which plays out in adopting a multicultural perspective of conflict resolution.
To prepare for this assignment:
• Select a conflict to use for this Assignment. It may be your Final Project conflict or another that interests you. It may be current or historical, and one which you know about personally or from the media.
• Review Chapter 27 in the course text, The Handbook of Conflict Resolution, paying particular attention to the theory and concepts for intercultural communication and their implications for conflict resolution. Also focus on the meaning, value, and implications of adopting a multicultural perspective in conflict resolution.
The assignment: (500 word minimum)
• Briefly describe the conflict that you selected for this Assignment, its central issues, and the parties involved.
• Explain what a multicultural perspective of conflict resolution is and how, specifically, it could contribute to the resolution of conflict, both in general and specifically with your conflict. Support your explanation with examples.
• Briefly describe two intercultural communication theoretical constructs or concepts, the awareness and understanding of which you think would be most significant in their effect on conflict, in general and specifically with your conflict. Explain how and why this awareness and understanding might improve the chances of the conflict being resolved and/or mitigate the negative aspects of the conflict. Reference the

 

Sample Solution

Alternative splicing is the process by which a large number of different mRNAs and proteins are produced from a comparably low number of genes, this occurs in most metazoans. It is believed that around 60% of human genes undergo alternative splicing and many genes have multiple transcripts produced via splicing, some genes have thousands of different transcripts that are able to be produced by this process. The production of these altered mRNAs and proteins can occur due to multiple different changes to the mRNA. One of the main alterations is the inclusion or exclusion of cassette exons. These are exons are not constitutive and are only sometimes included in the transcript. The length of exons can also be altered by changes of the location of one of the genes splice sites. These changes in splice site location can have many different effects on the protein produced from the transcript such as enzymatic activity and localisation within the cell. The process of splicing is directed by splice site sequences which are observed at the junction between the intron and exon. These splice sites are found at both the 5’ end and 3’ end of introns and both contain consensus sequences to which the spliceosome can attach. The spliceosome is a large macromolecular complex that assembles around the splice site from five small nuclear ribonuleoproteins as well as multiple accessory proteins Splicing occurs through a reaction which contains two transesterification steps which are catalysed by the spliceosome. (maybe insert more about mechanism) (need references)

Research by Webby et.al (2009) using liquid chromatography-mass spectrometry techniques found a link between Jmjd6 function and the RNA splicing mechanism. Jmjd6 was observed to hydroxylate lysine residues on a key splicing regulatory factor in humans called U2AF65. It was found that Jmjd6 hydroxylated two specific lysine residues which as Lys15 and Lys276. These findings suggest a role in the regulation of alternative splicing by jmjd6.

RNA polymerase pause release-

RNA polymerase II pausing occurs during early transcriptional elongation after the enzyme has bound the RNA strand. At this point further signals are required for elongation to continue. Until these signals are released the RNA polymerase remains stably bound to the RNA. After the signals are released the polymerase then progresses along the gene, terminates and eventually restarts transcription. The process of polymerase II pausing is prevalent in metazoans and has been suggested as a widespread mecha

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