Emergency department for hematemesis

“Live” presentation of content and scholarly source due during scheduled virtual meeting
Questions:

Read the scenario below and identify the likely digestive system disorder the patient is experiencing.
Explain the underlying pathophysiology (aka. cellular/tissue changes) and relate it to abnormal examination and diagnostic findings.
Explain additional diagnostic testing, medical treatment, and nursing care to treat the patient and/or prevent future complications.
Scenario:

A 52-year old female is in the emergency department for hematemesis. She reports vomiting a large amount of dark red blood and almost “passed out”. Her partner called 911 after finding her kneeling over the toilet and groaning. She was cooperative, but lethargic and weak. She had to be lifted by paramedics onto the gurney for transport. She reports weakness, fatigue, abdominal distention and “heaviness”, dyspnea, shortness of breath (SOB) with exertion, and an unintentional 15 lb. weight gain.

Past medical & family history

She was diagnosed with depression and alcohol dependence 5 years ago. She was prescribed paroxetine for depression and takes it as prescribed. She attended alcohol rehabilitation and remained sober for about 2 years, but began drinking alcohol again to cope with the stress during the COVID-19 pandemic. She has smoked half a pack of cigarettes daily since her early 20s. She has a history of hepatitis C infection 8 years ago. She has a history of breast cancer in situ and was treated with a right lumpectomy 6 years ago.

Her father died at the age of 58 from alcoholic liver disease; and he had a history of type 2 diabetes, hypertension, hyperlipidemia, and osteoarthritis. Her mother died at the age of 64 from a stroke; and she had a history of breast cancer and lupus. Her sister is alive at age 48 with a history of lupus and endometriosis.

Vital signs

Heart rate = 132 beats/min, regular
Respirations = 28 breaths/min, slightly labored
Oxygen saturation = 90% on 2L of oxygen via nasal canula
Temperature = 99.8° Fahrenheit (oral)
Blood pressure = 92/54 mmHg
Pain = 5/10 (epigastric)
Physical examination

Neurologic – lethargic, easily aroused, oriented, cooperative, sclera jaundiced
Skin – cool, dry, pale, intact, conjunctiva jaundiced, skin color appropriate for ethnicity
Abdomen – bowel sounds hypoactive. Abdomen slightly firm and distended. Abdomen tender in right upper quadrant. Enlarged liver palpable. Small amount of dark, yellow, clear urine.
Cardiovascular – heart rate rapid and regular. S1 and S2 heard. Peripheral pulses thready and 1+, pedal edema 1+, bilateral jugular venous distention present. No abnormal heart sounds.
Pulmonary – lung sounds clear in apices, but bases diminished with crackles; SOB with exertion
Musculoskeletal – full range of motion, strength 3/5 in extremities
Diagnostic test results

Chest x-ray – lungs with moderate pulmonary edema
12-lead electrocardiogram (ECG) – sinus tachycardia, no acute ischemic changes
Esophagogastroduodenoscopy (EGD; aka. upper endoscopy) – esophagus with 2 medium-sized varices at the proximal and mid esophagus with bleeding. No other abnormalities.
Computerized tomography (CT) scan of chest and abdomen – Enlarged liver with fibrosis, nodularity, and irregular contour. Esophageal thickening. No free air or other abnormalities.
Serum results – abnormal results and normal ranges below, all other results within their normal range
Blood urea nitrogen = 41……………………………..(6-20 mg/dL)
Creatinine = 2.8……………………………………………(0.9-1.3 mg/dL)
Total protein = 4.0………………………………………..(6.0-8.3 gm/dL)
Albumin = 2.7……………………………………………….(3.5-5.0 gm/dL)
Bilirubin (total) = 2.4…………………………………….(0.2-1.3 mg/dL)
Aspartate aminotransferase (AST) = 73……….(10-59 U/L)
Alanine aminotransferase (ALT) = 50…………..(10-40 U/L)
Ammonia = 92……………………………………………..(10-80 mcg/dL)
Red blood cells (RBC) = 3.9………………………….(4.2-5.4 x 1,000,000 cells/μL)
Hemoglobin (HGB) = 8.2……………………………..(14.0-17.0 gm/dL)
Hematocrit (HCT) = 26.7……………………………..(41-51%)
Platelets (PLT) = 112.4…………………………………(150-400 x 1000 cells/μL)
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Sample Solution

from the American culture. Most of them resided on the Pacific Coast, which was where most were afraid of an invasion by the Japanese. Americans became skeptical about whether these Japanese Americans were loyal to their race or country.

Roosevelt then passed Executive Order 9066, which stated that internment camps (left) were allowed in order to keep possible threats in their place. This led to evacuations of many Japanese people on the West Coast.

Korematsu v. The United States

Even though there were some Japanese Americans who were born in American and had US citizenship, they were still discriminated against. A Japanese American named Fred Korematsu didn’t want to split with his non-Japanese girlfriend simply because he was Japanese, so he was eventually arrested and forcibly put in an internment camp.

Korematsu’s civil rights were violated, however, the Supreme Court decided that these actions were justified because America was in a time of conflicts and small problems such as Korematsu’s could be put off.

War Refugee Board

Jewish Americans were aware of what was happening to their relatives in Europe, so they urged the US to take action and assist them. The US government knew the inhumane actions Hitler was executing, but no action was taken until 1944.

The War Refugee Board allowed Jews to seek refuge at safe centers or at US owned camps in Europe.

Zoot Suit Riots

In Los Angeles, California, there were two sides of a conflict: Mexican Americans and white Americans. Many Mexican American teenagers wore “zoot suits” which included a broad felt hat, a long suit coat, and loose pants. White Americans saw this style as gang-like, leading them to attack anyone wearing the fashion. The

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