Family’s medical history

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1. Do you know of anything in your family’s medical history that might predispose you to a higher
risk of cardiovascular disease, cancer, obesity, diabetes Type 2, osteoporosis, or any of the
other chronic health conditions with which certain foods or diet has been associated?
2. What are the barriers you see in your daily life that impact your ability to follow a “healthy
eating pattern”on a regular basis?Once these barriers are identified,you may be able to figure
out ways around them!
3. Reviewing the Macronutrient Distribution Report, does your average intake over this three
day period reflect “proportionality” as discussed in the Guidelines? (Remember that
proportionality refers to the amount of calories consumed from each macronutrient within the
total daily caloric intake.)
4. When considering the Intake Compared to DRI Report, are there specific nutrients that are
significantly under or over the DRIs? Consider micronutrients as well as macronutrients when
you are answering this question.
5. How does the My Plate report help you to evaluate your current diet?
6. Finally, set one realistic, achievable goal for bringing your current diet more into line with the
recommendations in the Dietary Guidelines. This goal should be short term – something you
can realistically achieve in the six weeks we have together. Make it small and doable within
the context of the barriers you outlined in #2.

Sample Solution

The latest advances in nanotechnologies, especially in nanoparticles, make them very promising in the delivery of therapeutics, drug discovery and diagnostics [13].
The delivery of therapeutic compound to the target site is a major trouble in the treatment of various diseases. A conventional application of drugs is characterized by limited effectiveness, poor biodistribution, and lack of selectivity [14]. The nanoparticles (NPs) as drug delivery systems may offer a number of advantages such as protection of drugs against degradation, targeting the drugs to specific sites of action, organ or tissues, and delivery of biological molecules such as proteins, peptides, and oligonucleotides.

Applications of drug nanoparticles include: both biodegradable nanoparticles for systemic drug delivery and nonbiodegradable nanoparticles for drug dissolution modification have been studied [15-18]. Proposed applications for drug nanoparticles vary from drug targeting and delivery [15, 17, 19-23] to even gene [24-26] and protein [27, 28] therapies. Administration of nanoparticles by, for example, parenteral [16] ocular [29-31] , transdermal [32], and oral routes have been studied. However, the oral route is still the most convenient, preferred, and in a lot of cases, also the

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