The first-line therapy for osteoarthritis is nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by blocking the production of prostaglandins, which are chemicals that cause inflammation and pain.

Sally expresses concern about all the recent news about heart problems and celecoxib (Celebrex). What information should be included in a teaching plan to help her understand about taking celecoxib and the benefits and risks?

Celecoxib is a type of NSAID that is generally considered to be safer for the heart than other NSAIDs. However, there is still some risk of heart problems associated with celecoxib, especially in people who are already at risk for heart disease.

The following information should be included in a teaching plan to help Sally understand about taking celecoxib and the benefits and risks:

• Celecoxib can help to reduce pain and inflammation from osteoarthritis.
• Celecoxib is generally considered to be safer for the heart than other NSAIDs.
• There is still some risk of heart problems associated with celecoxib, especially in people who are already at risk for heart disease.
• Sally should talk to her doctor about her individual risk of heart problems before taking celecoxib.
• Sally should take celecoxib exactly as prescribed by her doctor.
• Sally should stop taking celecoxib and call her doctor if she experiences any of the following side effects: chest pain, shortness of breath, or other heart problems.

Ibuprofen and celecoxib are both nonsteroidal anti-inflammatory drugs. Explain how they are similar and different.

Ibuprofen and celecoxib are both NSAIDs, which means that they work by blocking the production of prostaglandins. However, there are some important differences between the two drugs:

• Similarities:
  • Both ibuprofen and celecoxib are used to treat pain and inflammation.
  • Both drugs are available over-the-counter and by prescription.
  • Both drugs can cause side effects such as stomach upset, nausea, and vomiting.
• Differences:
  • Celecoxib is generally considered to be safer for the heart than ibuprofen.
  • Celecoxib is more expensive than ibuprofen.
  • Celecoxib has a longer half-life than ibuprofen, which means that it stays in the body for a longer period of time.

Overall, celecoxib is a good option for people with osteoarthritis who are concerned about the risks of heart problems associated with other NSAIDs. However, it is important to talk to your doctor about your individual risk factors before taking celecoxib.