Mrs. P. is an 80-year-old woman recently discharged from a 24-hour observation stay at the hospital after being diagnosed with acute bronchitis. She has a history of heart failure, hypertension, osteoarthritis, GERD, and hyperlipidemia. She has no history of smoking. While in the hospital she was prescribed doxycycline, prednisone 15 mg to taper, and a tiotropium inhaler. Her current list of daily medications prior to hospitalization includes metoprolol succinate 12.5 mg, pantoprazole 40 mg, atorvastatin 10 mg, lisinopril 10 mg, furosemide 40 mg, potassium chloride 20 meq bid, acetaminophen 650 mg bid for pain and tramadol 25 mg as needed. She lives alone but will reside temporarily with her daughter while she recovers. Her discharge report indicated resolving bronchitis, no exacerbation of heart failure, and stable arthritic pain. Today she reports 1 week after discharge with her daughter for a primary care appointment, and they both were concerned about the number of medications she was prescribed and wanted her medications reviewed. In further review, she was found to have lost weight over the past 6 months of 5 lbs and her current BMI is 25. She states that the weight loss may be due to a change to a healthier diet and reducing sodium as instructed. She also reports no symptoms of GERD for the past 6 months and minimal arthritic pain because of regular use of acetaminophen and daily walking in the halls of her independent living facility. Upon examination her lungs are clear to auscultation and no evidence of lower extremity edema.
Discuss the following:
1) In reviewing her medication list and current symptoms and clinical signs, which
medication could the nurse practitioner consider de-prescribing.
2) Once the patient has completed the prednisone taper, which medication could the nurse
practitioner begin to reduce given the patient’s reported symptoms.
3) Given the absence of an exacerbation of heart failure and compliance with a reduced
sodium diet, what other medication(s) adjustments could the nurse practitioner consider at
this time.
There are a few medications on Mrs. P.’s list that could be considered for de-prescribing.
It is important to note that these are just a few suggestions, and the final decision of which medications to de-prescribe should be made by the nurse practitioner after a careful review of Mrs. P.’s medical history and current condition.
Once Mrs. P. has completed the prednisone taper, the nurse practitioner could begin to reduce the lisinopril. Mrs. P.’s blood pressure is currently well-controlled, and she has no history of heart failure. Reducing the lisinopril could help to minimize the risk of side effects, such as dry cough and dizziness.
It is important to monitor Mrs. P.’s blood pressure closely after reducing the lisinopril. If her blood pressure starts to rise, the lisinopril dose can be increased or another medication can be added.
In addition to the medications mentioned above, the nurse practitioner should also consider de-prescribing any medications that are no longer necessary or that are causing side effects. The goal is to find a medication regimen that is effective and safe, and that minimizes the risk of side effects.
Discussion
The decision of which medications to de-prescribe is a complex one, and it should be made on a case-by-case basis. However, the principles outlined above can be used to guide the decision-making process.
It is important to consider the patient’s individual medical history, current symptoms, and clinical signs when making the decision to de-prescribe a medication. It is also important to monitor the patient closely after de-prescribing a medication to ensure that their condition does not deteriorate.
De-prescribing medications can be a safe and effective way to improve a patient’s quality of life. By carefully considering the patient’s individual circumstances, the nurse practitioner can help to ensure that the patient receives the best possible care.