1. Submit researched scholarly data for TWO MORE of the IS-related solutions that were selected.
2. Submit a minimum of TWO full pages of double-spaced text in the Body of the Text section for EACH ISrelated solution (four additional pages equalling eight full pages of text total).
Some suggestions on the types of data that you might include to build the paper are as follows:
-Describe how the information systems will benefit your company.
-Provide details and examples of applications and solutions offered by retail vendors.
-Describe the framework for each solution that the internal staff of your company might develop and implement.
-Present an account of the strengths, weaknesses, and cost considerations for those solutions.
-Identify and describe how a solution can provide a competitive advantage, influence strategy, affect
organizational performance, and increase operational efficiency
Look for dysmorphic features that would suggest a genetic syndrome. Cushingoid facies, hyperpigmented stretch striae and hypertension suggest cushing’s or exogenous steroid exposure. A hump on the back of neck and stretch striae may also be present in children with simple obesity. Dry skin or enlarged thyroid gland may suggest hypothyroidism and presence of acanthosis nigricans is an indicator of insulin resistance. Acne and hirsutism in girls could be due to PCOD. Shortening of 4th and 5th metacarpal should raise the suspicion of pseudohypoparathyroidism.
Look for gynecomastia in males. Genital examination for Tanner staging & evaluation of early puberty should be done. Undescended testes in males could be associated with syndromic obesity.
4) Laboratory Investigations:
Initial investigations include evaluation for cause and consequences of obesity. Specific testing for the endocrine disorders is done only if there is strong clinical suspicion. These are mentioned in Table 3. Genetic testing should be considered in children with early onset severe obesity, voracious appetites, family history of severe obesity and in those where a clinical suspicion of genetic obesity syndromes is present. Lab investigations currently available in India for monogenic obesity are; MC4R, Leptin and FTO gene. Leptin deficiency is rare and resistance is more common. TSH levels are often mildly elevated in obese children and are a major cause for referral.