The Molecular Diagnostics
A. You have been given the task of setting up a molecular diagnostics laboratory to provide pharmacogentic testing. What factors would you influence the scale and repertoire of tests you offer and give two specific example of genetic tests that are used to determine drug therapy?
B. Describe how fluorescence in situ hybridisation (FISH) is used in cancer diagnosis and prognosis.
C. Molecular techniques are being used increasingly in the diagnosis. Briefly describe how DNA technology is changing the practice of the disorder’s diagnosis.
D. Screening for genetic diseases has been influenced by DNA-based molecular techniques. Give two unrelated examples of how the use of molecular diagnostic has facilitated screening and how this has made a difference.
are many potential types of errors in survey sampling. According to Groves (1989)[see 1], the survey errors can be divided into two major groups: First, the errors of nonobservation where the sampled elements use only part of the target population, and the second one is the errors of observation, where the listed data deviate from the truth. Some examples of errors of nonobservation can be ascribed to sampling, coverage or nonresponse which is going to be analysed in the later part of this report. On the other hand, examples of errors of observation can be attributed to the interviewer, respondent or method of data collection. Both of our sources of obdurate errors can vigorously affect the accuracy of a survey. However, these errors cannot be eliminated from a survey but their effects can be reduced by careful devotion to an acceptable sampling plan. Some ways to reduce those errors are: callbacks (where the interviewer calls again the nonrespondents), offer rewards and motivation for encouraging responses, train better the interviewers, scrutinise the questionnaires to be sure that the form has been filled correctly and have an accurate questionnaire construction.