Case Study: Coagulation

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Nose BleedJessie was a typical 2-year-old who liked to try and spread his wings. He would run and fall throughout the house. On several occasions, with minor falls, a bruise would develop on his legs or arms. Jessie’s parent would often worry about being reported for child abuse because of the easy bruising that Jessie experienced.

At three, Jessie would complain that his ankles hurt. This was especially true after a hectic day of running and playing with other kids at the playground. Jessie’s parents wondered if he was simply trying to get attention. Which he usually did being an only child.

When Jessie was four, he accidentally ran into a small tree, hitting his nose. The nose bled excessively. Jessie’s mother tried to stop the bleeding, first with paper towels, which Jessie soaked through quickly, and then with a cold washcloth. Nothing seemed to help. Nervous about the amount of blood that Jessie was losing, his parents rushed him to the emergency room.

The emergency doctor ordered some blood work that included a Prothrombin Time (PT)and a Thromboplastin Time (PTT) test for clotting deficiencies. The site of the venipuncture for the blood draw, also took some time to stop bleeding.

An hour after the blood draw, the physician returned to the ER room to discuss the test results. Jessie’s PT results were normal but his PTT results were abnormal with an extended clotting time. The PTT clotting time was much longer than normal indicating the Jessie may lack of or decreased levels of a clotting factor.

Deliverables
Answer the following questions and save your responses in a Microsoft Word document. Provide a scholarly resource in APA format to support your answers.

Discuss which clotting factors the PT and PTT test evaluate and whether each test measures the intrinsic or the extrinsic pathways.
Describe the common coagulation pathway.
Based on Jessie’s test, which factor deficiency do you believe he has and why?
Jessie’s clotting factor disease is seen more often in males. Please explain why.
If both the PT and the PTT tests were abnormally long, which part of the coagulation pathway would be affected?

 

Sample Solution

Naïvety is best defined by a person with an extreme lack of judgment or experience in everyday situations. Throughout this journal, authors Amrish Patel and Edward Cartwright discuss how the beliefs of naïve and rational people affect not only their decisions and actions they chose but how they evolve as a person. Patel and Cartwright analyze how naïve viewers chose to believe in anything they are told without inquiring whether or not the statement was credible, and decide to view things only at their superficial appearance. Rational viewers, on the other hand, choose to view situations with a more realistic approach and make decisions based on reason rather than letting their emotions overcome them. Amrish Patel works in the Department of Economics at the University of Gothenburg working in both the behavioral economics and game theory fields, while Edward Cartwright works as Professor of Economics at De Montfort University. As a result of these various achievements and qualifications, these authors are very credible for this topic. The protagonist, Candide, is an extremely naïve character who is exceedingly vulnerable to the domination of the other strong-minded characters. Similar to Patel and Cartwright’s statements, naïve people allow others to influence their decisions due to their disregard for reliable sources.

Van Leeuwen, Marco H.D., and Ineke Maas. “Historical Studies of Social Mobility and
Stratification.” Annual Review of Sociology, vol. 36, 2010, pp. 429–451. JSTOR,
www.jstor.org/stable/25735086

Throughout the many eras such as the Byzantine, the Elizabethan, the Romantic, and many more, the ideas of a social hierarchy system have remained the same. However, the mobility between classes has dramatically changed through various time periods. Throughout this journal, authors Marco H.D. van Leeuwen and Ineke Maas discuss their historical research on social mobility and structure, as well as the shifts in the social imbalance in earlier years and what factors caused these outcomes. Marco H.D. van Leeuwen is an honorary research associate at the International Institute of Social History as well as a Professor of Historical Sociology in Utrecht. Ineke Maas is a Professor at the Department of Sociology at the Universiteit Amsterdam and studies trends in mobility throughout generations, in careers, as well as in marital situations. Due to their many qualifications, Leeuwen and Maas act as an exceptionally reliable source for my topic. This article connects to the Status Mobility and Reactions to Deviance and Subsequent Conformity journal by Elihu Katz, William L. Libby Jr., and Fred L. Strodtbeck because they both discuss the differences of social mobility throughout various eras.

Zollman, Kevin James Spears. “Social Structure and the Effects of Conformity.” Synthese, vol

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