Calcium and phosphate are hormonally regulated

 

• Analyze how calcium and phosphate are hormonally regulated and describe the pathophysiology, clinical manifestations, evaluation and treatments for hypercalcemia and hypocalcemia. • Describe the clinical manifestations, similarities, and differences of the following vitamin deficiencies: niacin, riboflavin (B2), thiamine (B1), folate, vitamin B12, vitamin B6, pantothenic acid (B5), biotin, vitamin C, vitamin K, vitamin E, vitamin A, and vitamin D.

Sample Solution

Calcium and phosphate are two important minerals within the body which need to be regulated at a homeostatic level in order for proper functioning of cells, tissues and organs. Mainly responsible for this regulation are two hormones; calcitonin secreted by the thyroid gland and parathyroid hormone (PTH) released from the parathyroid glands (Richardson et al., 2018). The balance between calcium, phosphorus and Vitamin D is maintained through complex mechanisms which provide feedback loops when one of these three becomes too high or low.

Hypercalcemia occurs when there is an excess of calcium in the blood usually due to overproduction or inadequate excretion of PTH leading to increased absorption from intestine as well as release of calcium stored in bones (Ayala-Castro & Moseley, 2020). Symptoms can range from nausea, vomiting, constipation and abdominal pain to confusion or muscle weakness depending on severity. Diagnosis involves measuring serum levels using laboratory tests such as ionized calcium along with evaluation of kidney function via urine output estimation tests while treatments options include hydration therapy with loop diuretics if dehydration is present as well as bisphosphonates or steroids that reduce bone resorption (Dardik et al., 2021).

Hypocalcemia on the other hand occurs when there is not enough calcium in circulation due to decreased production/secretion of calcitonin secondary to lack vitamin D intake or disease states such as hypoparathyroidism. It commonly presents with symptoms like anxiety, fatigue, irritability tremors along with tingling sensation around mouth area (Gonzales & Aguirre-Bahena, 2019). Diagnosed similarly by measuring levels using laboratory tests treatment generally includes oral supplementations such as Vitamin D3 plus Ca++ injections under certain cases where a quick correction is needed.

Section 1 – Project Objectives and by and large exploration approach

1.1 Reasons for Choosing the point and association

 

Enthusiastically for Finance and a craving for abundance creation through putting resources into productive endeavors, I have consistently attempted to evaluate and examine the exhibition stocks (organization’s) on the stock trade to see which may be productive. I therefor picked this subject since it would assist me with fostering the capacity to all the more likely examine organizations exhibitions, and furthermore to additional my vocation in finance. Throughout the span of my ACCA studies, I have been expected to assess the monetary exhibition (performing proportion examination) of associations, get ready and decipher budget reports (F5, F7, and F9), and to perform business examination. I therefor look to apply this information in a genuine circumstance subsequently this point appears to be great.

 

Humanity has for a very long time, relied upon the tremendous abundance of assets underneath the planet’s surface; from farming which was the significant action of early man to mining (the extraction of important minerals from the earth).

 

Mining has been a significant supporter the worldwide economy. A review distributed in 2013 observed that the worldwide gold industry’s commitment to the world’s economy was in excess of 150 nations around the world, as this area alone created more than $171 billions (Cecilia Jamasmie, 2015). As indicated by Mark Cutifani, CEO of AngloGold Ashanti (2012), “mining straightforwardly or by implication drives over 45% of the world’s total national output” (GDP) (Martin Creamer, 2012). This developing significance of the mining business to the worldwide economy was a critical driver to my choice of this area.

 

I additionally end up working in the ranger service area that likewise manages the extraction of normal assets, this nearness to nature additionally added to my decision of industry

 

I picked Fresnillo Plc on the grounds that it is perhaps of the biggest silver maker on the planet. The London-recorded organization works a few silver and mother lodes in Mexico. In spite of a drop in Mexican silver creation in 2014, the nation actually stayed the most elevated silver maker around the world, with Fresnillo at its front. The organization is versatile and has a designated creation result of in excess of 65 million ounces of silver by 2018 (Investing News Network, 2015).

 

1.2 Research points and goals

 

Dissect and assess the monetary exhibition of Fresnillo Plc for the 3 years finished 31st December 2017

Distinguish the elements that have affected the business and monetary execution of Fresnillo over these years These goals would be accomplished by giving solutions to the accompanying inquiries:

What has been the monetary presentation of Fresnillo Plc over the 3 years finishing 31st December 2017, in contrast with Tahoe Resources Inc.?

How has the qualities, shortcomings, potential open doors, and dangers to Fresnillo, impacted their exhibition (both monetary and nonfinancial) over the long term period?

How has Political, Economic, Social, and Technological elements impacted the presentation (monetary and nonfinancial) of Fresnillo?

1.3 Framework for RAP

 

The report examinations the monetary exhibition of Fresnillo Plc for the 3 years finishing 31st December 2017. This is worked with by the utilization of proportions, for example, productivity, liquidity, equipping, and financial backer proportions.

 

To more readily assess the presentation of Fresnillo, their exhibition is benchmarked against that of Tahoe Resources Inc.

 

The report then, at that point, goes further to dissect the effect of the business climate on the presentation of Fresnillo, by utilizing the SWOT system to analyzing its assets, shortcomings, open doors, and dangers. It additionally utilizes the PEST model to evaluate the effect of political, financial, social, and mechanical variables on Fresnillo Plc.

 

Section 2 – Information assembling and bookkeeping/business strategies

2.1 Sources of data

 

Data is fundamental to each examination venture, and given the vagueness in the idea of data it is fundamental to guarantee that data gathered is pertinent and suitable for some random exploration, investigation and so on. There are 2 fundamental data sources: essential and optional sources.

 

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