Case Study Analyzing Stuxnet

 

1. Explain the forensic technique Symantec researchers employed in order to receive the traffic sent by
Stuxnet-infected computers and describe what their analysis uncovered.
2. Identify what researchers were surprised to discover with Stuxnet’s malicious DLL file. Assess this significant
function of malware and what potential dangers it could present in the future.
3. Determine the primary reason that critical infrastructures are open to attacks which did not seem possible
just a couple of decades earlier.
4. Decide whether or not an appropriate case has been made in which Stuxnet was indeed a targeted attack
on an Iranian nuclear facility, based on the evidence and conclusions of the researchers. Provide your rationale
with your response.

Sample Solution

The advantages of pH-sensitive nanoparticles over other nanoparticles include: (a) the majority of carriers have been used as enteric-coating materials for a long time, and their safety has been approved. (b) The carriers show rapid drug release and then high drug concentration gradient as they undergo quick dissolving at definite pH and definite sites. The phenomenon is beneficial for the drug absorption. (c) They improve drug absorption comparing to the other conventional nanoparticles as they turn from the solid state to the hydrogel state at certain dissolution pH and so, the bioadhesion of the carrier to the mucosa becomes greater at specific fragment. (d) The drug stability can be enhanced more effectively using pH sensitive nanoparticles.
Different materials can be used for preparation of pH-sensitive nanoparticles:
a- pH-sensitive nanoparticles prepared from polyanions:
Such as Eudragits and HPMC phthalate.
b- pH-sensitive nanoparticles prepared from publications:
Chitosan is the main cationic polymer used to prepare pH-sensitive nanoparticles. It is the second most plentiful polymer in nature after cellulose.
c- pH-sensitive nanoparticles prepared from the mixture of polyanions and polycations:
Some techniques have been improved using the advantages of both polyanions and polycations [97,108, 113-116]. Most of the nanoparticle systems related consist of the positive-charged chitosan and a negative-charged polymer, such as Eudragit [97, 115, 117], poly (g-glutamic acid) [113, 114, 116], alginate [118], methacrylic acid [119] and polyaspartic acid [120].
d- Cross-linked polymers pH-sensitive nanoparticles (nanogels)
e- pH-sensitive nanomatrix prepared from Eudragit and nano porous silica:
A novel nanomatrix system for oral administration was developed in order to overcome the main problems of the nanoparticle colloid system which are its stability and scaling up. The system was composed of the pH-sensitive Eudragit and nano-porous silica previously used in pharmaceutical proce

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