Corporate Social Responsibility

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Introduce your understanding of Corporate Social Responsibility and choose any public company and analyze how do that company’s stakeholders view CSR. Then, in your paper, please explain how they are collaborating within the firm and their most important approaches. Also, what would you change if you were one of the executives in that firm?

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Corporate Social Responsibility

Corporate social responsibility (CSR) refers to strategies that companies put into action as part of corporate governance that are designed to ensure the company`s operations are ethical and beneficial for society. Tesla Inc.`s corporate social responsibility strategy addresses some of the major interests of the stakeholders of the automotive and energy solutions business. Tesla Inc. has a corporate social responsibility strategy that focuses on the nature of the business and its products. For example, the company`s electric automobiles are widely viewed as an answer to the negative impacts of cars that use internal combustion engines. In this regard, corporate citizenship is essential in the business. Investors and stakeholders have interests in profitability and growth of the business. Tesla`s corporate social responsibility approach addresses these interests through long-term strategies that aim to transform the automotive/transportation and energy market.

A standout amongst the most powerful discoveries for pharmacogenetics and its potential ability in clinical utility was the recognizable proof in 1977 of the hepatic cytochrome P450 oxidase that controls debrisoquine and sparteine metabolism (Mahgoub, 1977). Resulting populations and family ponders identified particular medication metabolism phenotypes and proposed that the “poor metabolism” traits were acquired in an autosomal recessive Mendelian style. The responsible enzyme, CYP2D6, was in the long run purified, cloned, and broadly sequenced and is presently accepted and believed to be straightforwardly involved in the metabolism of ~25% of all ordinarily utilized medications.

More than 80 variation CYP2D6 alleles have following been dicovered around the world, a hefty portion of which encode deficient enzyme activity, and these are deliberately classified by the Human Cytochrome P450 (CYP) Allele Nomenclature Committee (Sim and Ingelman-Sundberg, 2010). Imperatively, CYP2D6 is additionally inclined to copy number variations, including full gene duplication and deletion, which can significantly have influence on the interpretation of CYP2D6 genotyping, sequencing, and phenotype prediction. Since the beginning of discovering CYP2D6 and its critical part in drug metabolism, CYP2D6 genotypes have been associated with four general metabolism phenotypes: poor, intermediate, extensive and ultrarapid. Since clinical DNA-based CYP2D6 testing is accessible, interpretation of a patient’s genotype normally incorporates one of these predicted metabolism phenotypes; nevertheless, it ought to be emphasized that this is just an expectation and not in light of individual pharmacokinetic measurements. Notwithstanding CYP2D6, numerous other vital CYP450 genes have been found, and polymorphic variation alleles keep on being recognized in various populations. Notable discovery incorporates two enzymes from the CYP2C subfamily: CYP2C9 and CYP2C19. The CYP2C19*2 (c.681G>A) variation allele was initially identified as the reason for impeded mephenytoin metabolism (de Morais et al., 1994), and from that point forward, various other

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