Factors That Influence Disease

In clinical settings, some of the most common questions that patients ask are Why do I have this? What caused this disorder? Will it ever go away? These emotional questions can be difficult to ask and to answer. However, for patients to come to terms with their diagnoses and adhere to treatment plans, they must have an understanding of factors that might have caused, or continue to impact, their disorders. As an advanced practice nurse, it is important that you are able to explain disorders, associated alterations and symptoms, and changes that might occur within your patients’ bodies.

To Prepare

Review this week’s media presentation with Dr. Terry Buttaro. Reflect on the importance of developing an in-depth understanding of pathophysiology.
Select a disorder from the following list:
Adrenal insufficiency (Addison’s disease)
Atherosclerosis
Cholelithiasis (gallstones)
Colon cancer
Cystic fibrosis
Hemophilia
Nephrolithiasis (kidney stones)
Osteoporosis
Parkinson’s disease
Tuberculosis
Select one of the following patient factors: genetics, gender, ethnicity, age, or behavior. Reflect on how that factor might impact your selected disorder, as well as potential associated alterations and symptoms.
Identify the pathophysiology of the associated alterations, including the normal and altered cellular function. Consider both intra- and extra-cellular changes that occur.

 

 

Sample Solution

Factors That Influence Disease

Cystic Fibrosis (CF) is an inherited disorder that causes severe damage to the lungs, digestive system and other organs in the body. CF affects the cells that produce mucus, sweat and digestive juices. Every person has two copies of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. A person must inherit two copies of the CFTR gene that contain mutations, one copy from each parent, to have cystic fibrosis. CF carriers do not have the disease but can pass their copy of the defective gene on to their children. Mutations in the CFTR gene cause the CFTR protein to malfunction or not be made at all, leading to a buildup of thick mucus, which in turn leads to persistent lung infections, destruction of the pancreas, and complications in other organs.

 

Correspondence of E.coli Outbreak in the Community

Development of the event of E. coli in the network As a human administrations director in the event of disease, I will take every single essential measure to speak with youngsters, guardians and clinical staff in an ideal and powerful manner take. My first concern is to disengage maladies however much as could be expected and to permit those effectively tainted to get the treatment they need (Graham-Clay, 2005). On the off chance that illnesses, for example, Escherichia coli happen in a neighborhood secondary school, we will promptly illuminate the clinical staff.

Escherichia coli contaminations from food cause genuine disease, which can prompt genuine ailment and here and there death. Since treatment is constrained, avoidance by overseeing food handling is imperative to control the event of these infections. In any case, E. coli is profoundly flexible, versatile, can convey and move DNA, makes new strains and is impervious to current preparing and control strategies. Further exploration is required around there before unlimited oversight is gotten.

Intestinal hemorrhagic E. coli is a perceived ailment because of the event of a financially accessible inexpensive food burger. Manifestations of bacterial disease by E. coli incorporate serious loose bowels, generally blood, stomach agony and spewing. Kids younger than 4 are bound to build up this ailment. Related nourishments incorporate uncooked meat, unsterilized milk, juice. Sullied water can be brought about by fecal tainting of individuals who have pathogens. Indeed, even disinfectants utilized in certain items will most likely be unable to adequately wreck pathogens. Consequently, it is suggested that individuals with handicaps in the safe framework and other high-hazard bunches abstain from eating sprouts. Chloride-rewarded sprouts are still connected with the advancement of E. coli and Salmonella (Taormina and Beuchat 1999). Treatment incorporates steady consideration and checking of renal capacity (CDC, 2001). By and large, antibodies are contraindicated. The final product of kidney disappointment might be demise

MRSA disease was initially restricted to emergency clinics and unique nursing home, particularly individuals who are frail in the resistant framework. Since the 1980s, network type cases and pandemics have likewise been accounted for. The cases got in the network are cases not identified with hospitalization or dialysis, medical procedure or catheterization in the previous year. These diseases for the most part happen in other solid individuals and are probably going to be constrained to skin contaminations. Notwithstanding, over the previous decade, the expanded pathogenicity of MRSA microscopic organisms has brought about progressively genuine, now and then lethal network diseases. As of late, MRSA has been found in eatable creatures, and a few episodes are “food prompted” or foodborne. In one such episode, tainted individuals created run of the mill side effects of foodborne infections, for example, heaving and stomach cramps.

 

 

 

 

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