1. Describe how foods may affect HIV treatment (provide at least 2 examples).
2. Explain how to prevent opportunistic infections through their diet in people living with HIV.
3. Describe the type of cancer frequently associated with HIV and explain how this cancer’s symptoms may cause anorexia on those with HIV (see page 663 in your textbook).
How foods may affect HIV treatment
Example 1: Grapefruit
Grapefruit can interact with some HIV medications, such as protease inhibitors and integrase inhibitors. These medications are broken down by a liver enzyme called CYP3A4. Grapefruit can inhibit CYP3A4, which can lead to higher levels of HIV medication in the blood. This can increase the risk of side effects from the medication.
For example, the protease inhibitor atazanavir can cause jaundice, a yellowing of the skin and eyes, when taken with grapefruit. The integrase inhibitor raltegravir can cause nausea, vomiting, and diarrhea when taken with grapefruit.
Example 2: Garlic
Garlic can interact with some HIV medications, such as protease inhibitors and nucleoside reverse transcriptase inhibitors (NRTIs). These medications are broken down by a liver enzyme called CYP2C9. Garlic can induce CYP2C9, which can lead to lower levels of HIV medication in the blood. This can reduce the effectiveness of the medication and increase the risk of HIV viral resistance.
For example, the protease inhibitor indinavir can cause decreased levels of indinavir in the blood when taken with garlic. The NRTIs tenofovir and emtricitabine can cause decreased levels of tenofovir and emtricitabine in the blood when taken with garlic.
How to prevent opportunistic infections through diet in people living with HIV
A healthy diet is important for everyone, but it is especially important for people living with HIV. A healthy diet can help to boost the immune system, prevent opportunistic infections, and improve overall health and well-being.
People living with HIV should eat a variety of nutrient-rich foods from all food groups. This includes fruits, vegetables, whole grains, lean protein, and low-fat dairy.
Some specific foods and nutrients that are important for people living with HIV include:
In addition to eating a healthy diet, people living with HIV should also take a multivitamin supplement. A multivitamin supplement can help to ensure that they are getting all of the nutrients they need.
Type of cancer frequently associated with HIV
Kaposi’s sarcoma (KS) is a type of cancer that is frequently associated with HIV. KS is caused by a virus called human herpesvirus 8 (HHV-8). HHV-8 is a sexually transmitted infection (STI).
KS can develop anywhere on the body, but it is most common on the skin, mouth, and genitals. KS can appear as red, brown, or purple bumps or lesions.
How KS symptoms may cause anorexia on those with HIV
KS can cause a number of symptoms that can lead to anorexia, including:
In addition, KS can cause disfigurement, which can lead to social isolation and depression. These factors can also contribute to anorexia.
Treatment for KS
Treatment for KS depends on the stage of the cancer and the patient’s overall health. Treatment options include:
Conclusion
Foods can affect HIV treatment in a number of ways. For example, some foods can interact with HIV medications, which can reduce their effectiveness or increase the risk of side effects. Other foods can boost the