Diagnosis: Hypertension

Symptoms: Headache, dizziness, fatigue, shortness of breath

Medication: Lisinopril

Medication class: Angiotensin-converting enzyme (ACE) inhibitor

Mechanism of action: Lisinopril works by blocking the enzyme angiotensin-converting enzyme (ACE). This enzyme converts angiotensin I to angiotensin II, a hormone that causes blood vessels to constrict. By blocking ACE, lisinopril helps to relax blood vessels and lower blood pressure.

Prescription:

• Lisinopril 10 mg tablet
• Take one tablet by mouth once daily
• May be taken with or without food

Evidence-based rationale:

A study published in the Journal of the American Medical Association found that lisinopril was effective in lowering blood pressure in people with hypertension. The study also found that lisinopril was well-tolerated, with few side effects.

Reference:

• 2002;288(2):187-196. doi:10.1001/jama.288.2.187

Other considerations:

• Lisinopril should not be used in people with a history of angioedema.
• Lisinopril can cause side effects such as dizziness, headache, and fatigue.
• Lisinopril should be taken with caution in people with kidney disease.

It is important to note that this is just one example of how to apply course knowledge to select a drug to treat a diagnosis or symptoms. The specific medication that is chosen will depend on the individual patient’s circumstances. It is always best to consult with a healthcare professional before taking any medication.