Mental health implications

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focus on any aspect that feels meaningful and interesting to you.

 

the various mental health implications
the economic implications
suicide
addiction
families living in tight quarters and complicated family dynamics
the college experience and what this means now and later
ageism and the treatment of the elderly
expecting a baby at this moment in history
relationships and intimacy now (people away from boyfriends and girlfriends, the toll on marriages, etc)
unemployment
self-harm
the trappings of domestic violence and incest and assault amidst quarantine
health care
effects on friendships
technology

Sample Solution

The World Health Organization (WHO) recognizes the importance of psychological well-being, defining health as “a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity” (WHO 2003). In 2018, of the estimated 792 million people worldwide living with mental or behavioral disorder (roughly 10.7% of the global population), 178 million were drug or alcohol dependent, 20 million were diagnosed with schizophrenia, and 264 million suffered from depression (Ritchie, H., Roser, M., 2018). While it is often overlooked as a public issue due to a historical focus on communicable and more immediately life-threatening diseases, such as HIV/AIDS and malaria, mental health has profound effects on an individual`s quality of life, physical and social well-being, and economic productivity (Ibid).

a microtubule related protein significant for the security of axonal microtubules. Tau hyperphosphorylation hinders its limiting to microtubules, changing the dealing course for particles which may eventually prompt synaptic degeneration (13, 14). Diabetes actuates tau hyperphosphorylation in the mind, with respect to model in the hippocampus (15), and proteolytic tau cleavage (16), being the two cycles occuring in Alzheimer’s sickness (17). Hyperglycemia and insulin brokenness might prompt tau changes, and consequently may assume a part for the expanded rate of Alzheimer’s sickness in diabetic patients (16). Tau adjustment debilitates axonal vehicle through microtubule game plan disturbance and by impeding axonal dealing course, which can finish in synaptic capacity changes and ensuing neurodegeneration (18, 19). In Alzheimer’s illness, glycation of tau might settle matched helical fibers conglomeration prompting tangle development (20). All things considered, comparable cycles might be occuring under diabetes.

Neurofilaments

Neurofilaments (NF) are the transitional fibers (10 nm) found explicitly in neurons that collect from three subunits in view of sub-atomic weight: NF-L (70 kDa), NF-M (150 kDa), and NF-H (200 kDa) (21). Neurofilaments need by and large extremity upon gathering and for the most part give neuronal primary adjustment and control axonal development (22). Collection of neurofilaments is a typical marker of neurodegenerative infections (23). Strange NF articulation, handling, and design might add to diabetic neuropathy, since decreased blend of NF proteins or development of erroneously related NFs could seriously disturb the axonal cytoskeleton (24).

Neurofilament mRNAs are specifically diminished in diabetic rodents and modifications on p

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