Nursing research article (Ion Channels)

 

Compare and contrast the two different major classes of ion channels.
Explain the difference between full agonists, partial agonists, antagonists, inverse agonists.
Responses need to address all components of the question, demonstrate critical thinking and analysis and include peer-reviewed journal evidence to support
the student’s position.
Please be sure to validate your opinions and ideas with in-text citations and corresponding references in APA format.
Please review the rubric to ensure that your response meets the criteria.
Estimated time to complete: 3 hours
cholarly resource, ideally within the last 5 years. Journals and websites must be cited appropriately. Citations and references must adhere to APA format

Sample Solution

The two major classes of ion channels are voltage-gated and ligand-gated ion channels. Voltage-gated ion channels open in response to changes in membrane potential, while ligand-gated ion channels open when a certain molecule binds to them. In terms of structure, voltage-gated ion channels are made up of four subunits that form a central pore through which ions can pass (Heger et al., 2020). Ligand gated ion channels also have four subunits but they form a deep cleft rather than a pore (Rudenko et al., 2021).

In terms of function, voltage-gated and ligand gated ion channel exhibit distinct behaviors. Voltage gating allows for rapid signaling between cells due to the fact that it only requires an electrical signal from one cell in order to open the channel on the receiving end (Xu & Catterall 2019). In contrast, ligand gating requires binding with specific molecules such as neurotransmitters or hormones before the channel opens which makes it slower than voltage gating but more precise since this ensures only specific molecules can activate the channel (Cui et al., 2020).

Overall, both types of ion channels play important roles in cell communication by allowing for passage of ions across membranes. The main difference between them is that one is triggered by electrical signals while other needs binding with specific molecules. As such, understanding how these two different types work is essential for being able to effectively modulate biological processes.

 

when predicting attitude stability and the corresponding behavior and judgments of those behaviors. Moreover, Gantman and Van Bavel (2014) found evidence for a moral pop-out effect, such that participants were more likely to recognize moral words over nonmoral words in a lexical decision task.

 

 

With regard to group evaluations, it has been shown that moral judgments of one’s ingroup are more important than judgments of competence or sociability (Leach, Ellemers, & Barreto, 2007). Perceiving one’s ingroup as moral has been shown to lead to more positive outcomes of a group’s self-concept, such that positive moral evaluations of one’s ingroup leads to less distancing from that group and greater group identification (Leach et al., 2007). This line of research further extends to the evaluation of outgroups, with the main finding that moral traits are weighted more heavily when members of one group form impressions about an outgroup (Brambilla et al., 2013a). A limitation of this line of research is its focus on conscious, controlled perceptions of morality. Unconscious perception enjoys an extensive influence on social behavior (e.g., Greenwald & Banaji, 1995), and as such studying morality at the unconscious level may reveal interesting differences in explicit versus implicit evaluations of outgroups.

While previous research has provided a solid foundation for understanding just how important moral judgments are to individuals, more work needs to be done to fully examine how quickly moral judgments are made. Limited work has studied the role of implicit cognition in moral judgments, though there is reason to believe that moral judgments may be susceptible to nonconscious influences (e.g., Ma, Vandekerckhove, Baetens, Van Overwalle, Seurinck, & Fias, 2012; Willis & Todorov, 2006). Given that judgments of morality are deemed to be more relevant than other traits when judging whether a target represents a threat (Brambilla et al., 2013b; Willis & Todorov, 2006), we contend that research into the implicit attribution of moral personality traits is warranted to delineate whether morality is attributed automatically or through cognitive processes. This led to our first hypothesis, which predicts that participants will be more likely to recognize moral (versus nonmoral) traits

Spontaneous Trait Inferences

A spontaneous trait inference (STI) occurs when an individual makes a nonconscious, unintentional judgment about the character of another individual (Winter & Uleman, 1984). These inferences occur

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