Programmatic Knowledge

 

 

reflect on your internship experience by creating an internship brief and executive summary. Your internship brief will look at how
the things you learned in the classroom translated to a real-world work setting, as well as what experiences, skills, and knowledge were evidenced in either the
classroom or the work environment that were never revealed in the other. The executive summary will focus on your accomplishments and insights during your
academic and work experience.
I. Your Place in the Sports Industry
A. Host Company
i. Describe the organization where you are doing your internship and explain why you chose this company.
ii. Diagram the organizational structure of your host company location. Include an organizational chart that shows management positions
and departments and where you are in the organization.
iii. Examine the interrelationships of functional areas in the company and how they work together.
B. Duties and Responsibilities Within the Organization
i. Compose a job description of your internship with details of specific duties and required knowledge.
ii. Relate what you learned/accomplished during this internship and how it will benefit your future goals.
C. Identify New Job Opportunities
i. Prepare targeted resumes and cover letters for three actual jobs you are interested in. Include the job posting for each.

 

 

 

 

II. Applying Programmatic Knowledge
A. Explain how the projects in which you were involved allowed you to demonstrate your knowledge, skills, and abilities (KSAs) in meeting the
outcomes of your program.
B. Describe the differences between the theories you learned in the classroom and the workplace practices in this internship experience. What
were the reasons for these differences? Support your response with examples.
III. Reflection
A. Describe a situation or event that took place during your internship that you had to respond to. How might you respond differently to that
situation in the future? Explain why.
B. If you had the opportunity to do this experience over, how and why would you approach it differently?
C. What would you like to have accomplished that you were unable to do because of time, other priorities, and so on? For example, was there a
project or another opportunity you were involved in that you were unable to finish? Support your response with examples.
D. Considering your host company’s structure, propose how the entity could enhance interdepartmental synergies. Support your response with
examples.

 

Sample Solution

There are more than 30 million single-nucleotide polymorphisms that are like a finger print of genetic code in human genome(37). International Haplotype Mapping Project characterizes these SNPs in variety of population for public usage(38). Researchers can use these databases to identify association between disease risk .disease studies and genome- wide association studies linked by commercially available microarrays (SNP chips)(39). When specific allele of a SNP is present , a fluorescent signal is produced by using allele specific oligonucleotide probes for SNP arrays and array have skill of analyzing up to 1 million SNPs in a single sample(40). Also allelic imbalance, copy number variation, or loss of heterozygosity of cancer genome can be screened by SNP array.

Microarray analysis

Expression levels of thousand gene in cancer is analyzed with single experiment of microarray. Microarrays that are chips have immobilized capture molecules serve as probes to bind fluorescently labeled targets prepared from the two samples for comparing (41). These capture molecules can be oligonucleotides or cDNA. MRNA, miRNA, DNA and protein microarrays are most popular analysis. Gene expression profiling has been used for catogarizing unique subtypes of cancer, identifying invasive and non invasive cancer type’s phenotype, forecasting prognosis and response to treatment and risk of recurrence(42). New miRNA microarray platform data’s can be used as a cancer biomarker. To classify patients prognostic groups and treatment subgroups, miRNA signatures is used. Also misroarray is used to determine epigectic alteration that is contributed to tumorigenesis and direct to manage patient(43).

Proteomics by mass spectrometry

Changing of protein profiles in cancer cell is important to determine new biomarker and might help to classify of tumors subtypes(44). Proteomic analysis have more advantage than measurement of mRNA. Because protein is the final effector molecule and their level can not overlap the level of mRNA due to the posttranscriptional modifications(45). In addition to that , protein-protein interactions contribute to cellular pathways and carcinogenesis. Proteins are quanrified in mass spectrometry according to their mass to

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