Protein fragment

 

1. Identify the source of your sequence and the location of the fragment represented by this sequence in the protein.
2. If the source protein is not annotated, find a similar annotated protein to infer the biological significance of your fragment.
3. Check if the three-dimensional structure of your fragment is known.
4. Predict secondary structure for the selected sequence.
5. Predict three-dimensional structure for the selected sequence using homology modeling.
6. Analyze the quality of your model using one of the structure assessment tools.
7. Provide structural classification for your model.
8. Create a visualization of your model highlighting and annotating one of the important molecular or biological features.
9. Compare predicted secondary structure with the secondary structure in 3D model and interpret the result

Sample Solution

racteristics, the experience, individual characteristics and abilities of the pioneer, and the third are part attributes, the inspiration, expertise and experience levels of gathering individuals (Chelladurai and Madella, 2006). The situational attributes and part qualities have a necessary way of behaving to guarantee most extreme gathering execution, they additionally have a favored way of behaving to guarantee the fulfillment of gathering individuals, assuming that the pioneers genuine way of behaving matches both the expected way of behaving and favored conduct of the circumstance the result is greatest gathering execution and fulfillment. Nonetheless, in the event that the gathering are not performing and accomplishing objectives or are not fulfilled or both, then the pioneer can change their genuine way of behaving to work on this. Pioneers ready to screen execution and fulfillment, and figure out what is expected to revise going on will accomplish ideal gathering execution in Chelladurai’s model. The one limit of Chealldurai’s model is that it accepts the pioneer is in a place of complete positional control over the gathering, and can execute any initiative style fitting their personal preference without requirements. Positional power is the power and impact a pioneer has over a gathering, assuming the pioneer has positional power, they will actually want to carry out the initiative style they best see fit for the circumstance. Positional power can’t be estimated or measured, making it profoundly vague and difficult for a pioneer to comprehend whether they have it or how then can acquire it. It turns into the obligation of the association to have strategies set up to give pioneers some positional power, typically by laying out a reasonable hierarchal construction. By laying out a progressive system, the pioneer is seen by the gathering to have the option to set expectations and expect consistence from them giving the pioneer real power (French and Raven, 1959). Besides, by furnishing the pioneer with the capacity to compensate consistence and rebuff resistance from the gathering, the pioneer has reward and coercive power (French and Raven, 1959). To acquire total control over the gathering the pioneer should acquire the trust and conviction of the gathering that they are fit for progress, by guaranteeing the gathering are both fulfilled and meeting execution objectives. The significance of laying out an order became clear during the arranging phase of the open air administration course for the red group, the organizers inside the group accepted positions of authority however couldn’t acquire positional power because of the group being a friend bunch (Pettinger, 2007). The pioneers chose had little power and impact over the gathering as everybody was seen to have similar position, status and occupation, thus the pioneers had none of French and Ravens five bases of force (Pettinger, 2007). The outcome was pioneers with no positional control over the gathering, so couldn’t immediate the gathering with the technique for authority expected for the circumstance. The errand had critical limitations, especially a brief period of time and an enormous gathering size, for

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