Target Organ Toxicity

# Describe organ-specific toxicity endpoints
# Analyze target organ toxicity using the CompTox database and the IARC monographs
1: Using the resources provided below, look up information pertaining to target organ toxicity for your selected
topic. You will be graded on clarity and the mechanics of writing as well.
2: Using the information provided in Section 3, please look up your chosen toxicant in IARC. List the
classification (if there is one) for your toxicant. Discuss what this means in regard to the risk of cancer posed by
your chemical.
3: Using the lessons from the tutorial, search for the chemical you have selected.
4: Using the information from CompTox, summarize what you have learned about your chemical, specifically
mentioning information relevant to target organ toxicity. Your answer should include how these target organs
were identified, and in what models, as well as any limitations you might see with the data.
5: Using the information from CompTox, discuss the cancer classification between IRIS and IARC. If they are
different, discuss why different classifications may have been given to the same chemical.

 

Sample Solution

n the system. The manager and the leader of Vodafone focus on improving the process to detect the error, prevent and to reduce the errors. Six Sigma helps the manager and leader to approach every employees group of the Vodafone with consistent and clear methodology. The manager and leader focus on the manpower of the organization and motivate them to reach the objective of the system process in Vodafone. Six Sigma analyze, improve and control the process to achieve the goal of organization.

The manager’s role of Vodafone in Six Sigma:​​​

• Significant technical accuracy on the process.
• Administrative ability to lead their employees in every level of the system.
• Attention to all technical process and other planning process in the system.

The leader’s role of Vodafone in Six Sigma:

• Removes the barriers in the system to complete the project successful.
• Engages with the team for the continual growth and development of the organization.
• Efficient in working alongside the team to reduce the errors and improves team value during the business process.

Total quality management

Total quality management plays vital role in Vodafone to reach the long-term success through customer satisfaction. The manager and the leader use strategy, data and communicate to integrate the quality of the Vodafone. Total quality management theory is a customer focused management concept and employee involvement in the system. The manager and the leader of the Vodafone have strategic and systematic approach on the system for the continual improvement of the organization. The leader and the manager communicate with all level of employee for the effective method process to achieve the business objective.

The manager’s role of Vodafone in Total Quality management:

• Implementing the strategy and training the employees for the new decision of the organization.
• Recognizing and rewarding the employees for their effective work in the organization.
• Presenting planning and results to the employees in the system and their individual performance for the organization.

The leader’s role of Vodafone in Total Quality management

• Monitors the system for implementing the strategy to achieve the business goal.
• Creates trust among all the employees of the organization.
• Responsible for problems and achieving the goals of the process.

M3 Discussing how leaders and manager can improve the efficiencies of operational

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