Write a 1000 word essay that analyzes “The role of any chosen pathogen in human health and disease and public health” I chose E. Coli. paper must include the following: Appropriate microscopic, cultivation and non-cultivation methods for the chosen pathogen Importance of plasmids in bacterial genetics and in genetic engineering Human / microbe relationships Analysis of the virulence factors of microorganisms (include public health importance) Prevention and treatments strategies 5 references.
“The role of any chosen pathogen in human health and disease and public health”
Escherichia coli (E. coli) is a bacterium that is commonly found in the gut of humans and warm blooded animals. Most strains of E. coli are harmless. Some strains however, such as Shiga toxin-producing E. coli (STEC), can cause severe foodborne disease. It is transmitted to humans primarily through consumption of contaminated foods, such as raw and undercooked ground meat products, raw milk, and contaminated vegetables and sprouts. STEC produces toxins, known as Shiga-toxins because of their similarity to the toxins produced by Shigella dysenteriae. STEC can grow in temperatures ranging from 7 degrees Celsius to 50 degrees Celsius with an optimum temperature of 37 degrees Celsius (WHO). E. coli 0157:H7 is the most important STEC serotype in relation to public health. The prevention of infection requires control measures at all stages of the food chain, from agricultural production on the farm to processing.
mprove upon its current formula. Companies will most likely try to profit as much as possible while they are uncontested rather than invest more money to improving the drug since there possibly could be a minimal return on their investment.
Most importantly, we recognize the important role that healthcare providers play in this system. ****
4.Select the evaluation criterion
The high cost of prescription drugs not only negatively affects the clinical world but it causes the economy to suffer as well. Many Americans today currently have coverage for drugs through Medicare drug benefit and the Patient Protection and Affordable Care Act where more drug expenses have been seen. The private insurers have also increased several aspects of purchasing drugs such as increasing deductibles, increasing co-payments, and even added a payment tier. The payment tier is only for particular specialty drugs where individuals are required to pay co-insurance instead of regular co-payment. All of these implications have helped slow the long-term growth of medical expenses but in doing so we have lost the use of effective medications. Many individuals in American admit to not taking their prescription drugs as they were told to because they simply cannot afford them. In other studies, patients were prescribed a more expensive brand name drug rather than the cheaper generic drug and there was less compliance seen. As a consequence, “Nonadherence due to all causes has been established to contribute to $105 billion unavoidable health care costs annually” (Kesselheim et al).
Another consequence includes the use of coupons to reduce the price for drug costs which may initially seem like a good idea but in the end increases healthcare spending. The use of coupons will most likely leave the insurer choosing the higher priced drug. This has become rather common for the costly brand name drugs even when there’s less expensive generic drug alternatives available.
Within healthcare budgets, many components within often have to be decreased or increased. States with more costly drugs in the Medicare programs often have to reduce other services or increase health care eligibility requirements. For example, there are several states with Medicare programs that have policies that restrict sofosbuvir, an antiviral medication, that include denying coverage for any individual that uses alcohol or drugs (Kesselheim et al).
• Analytic- what are the consequences?
• Evaluative- value judgements about consequences
•Efficiency—maximize satisfaction(utility)
•Equity—maximize equality, fairness, social justice